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PD-1 inhibitor nivolumab monotherapy has been provento improve prognosis in HCC, and the addition of CTLA-4 inhibitor ipilimumab seemed to augment the impact, suggested by elevated ORR and OS in the combination group (Yau et al., 2022)

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Months 9-12: Approaching Maintenance (2.4 mg dose) Average weight loss: 13-15% cumulative by month 12 (26-30 pounds for a 200-pound person) Around month 6-7 (week 20-24), youll reach the maximum maintenance dose of 2.4 mg weekly

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